Blood and brain mercury levels after chronic gestational exposure to methylmercury in rats
نویسندگان
چکیده
منابع مشابه
Brain and blood mercury and selenium after chronic and developmental exposure to methylmercury.
Fish contain methylmercury and the potentially protective element, selenium. Blood and brain concentrations of these elements were determined in female rats after consuming AIN-93-based diets containing 0.06 or 0.6 ppm of selenium (Se) and drinking water containing 0, 0.5, or 5 ppm of mercury as methylmercury (MeHg) for 6 or 18 months. Brain and blood concentrations of mercury and selenium were...
متن کاملOrganic and Inorganic Mercury in Neonatal Rat Brain after Prenatal Exposure to Methylmercury and Mercury Vapor
BACKGROUND Many populations are exposed to multiple species of mercury (Hg), predominantly organic Hg as methylmercury (MeHg) from fish, and inorganic Hg as Hg vapor from dental amalgams. Most of our knowledge of the neurotoxicity of Hg is based on research devoted to studying only one form at a time, mostly MeHg. OBJECTIVES In this study we investigated the effects of prenatal exposure to Me...
متن کاملThe relation between mercury levels in brain and blood or cerebrospinal fluid (CSF) after mercury exposure.
Rabbits were exposed to elemental mercury (Hg degrees) vapor, methyl mercury (MeHg) and HgCl2 respectively, and the relationship of mercury concentration in brain to that in blood or cerebrospinal fluid (CSF) was investigated after the termination of exposure. At one day post-exposure, the ratio of mercury concentration in brain (microgram Hg/g) to that in blood (microgram Hg/g) was approximate...
متن کاملHair Mercury Levels in Six Iranian Sub-populations for Estimation of Methylmercury Exposure: A Mini-review
Background: Mercury is widespread and persistent in the environment. One organic form of mercury, Methylmercury (MeHg), can accumulate in the food chain in aquatic ecosystems and lead to high concentrations of MeHg in fish, which, when consumed by humans, can result in an increased risk of adverse effects. Currently, the Joint FAO/WHO Expert Committee on Food Additives (JECFA) has established...
متن کاملGestational Mercury Vapor Exposure and Diet Contribute to Mercury Accumulation in Neonatal Rats
Exposure of pregnant Long-Evans rats to elemental mercury (Hg0) vapor resulted in a significant accumulation of Hg in tissues of neonates. Because elevated Hg in neonatal tissues may adversely affect growth and development, we were interested in how rapidly Hg was eliminated from neonatal tissues. Pregnant rats were exposed to 1, 2, or 4 mg Hg0 vapor/m3 or air (controls) for 2 hr/day from gesta...
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ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 1999
ISSN: 1096-6080,1096-0929
DOI: 10.1093/toxsci/50.1.106